J Ethnopharmacol. 1986 Jun;16(2-3):117-51.
Grindlay D, Reynolds T.
The mucilaginous gel from the parenchymatous cells in the leaf pulp of
Aloe vera has been used since early times for a host of curative
purposes. This gel should be distinguished clearly from the bitter yellow
exudate originating from the bundle sheath cells, which is used for its
purgative effects. Aloe vera gel has come to play a prominent role as a
contemporary folk remedy, and numerous optimistic, and in some cases
extravagant, claims have been made for its medicinal properties. Modern
clinical use of the gel began in the 1930s, with reports of successful
treatment of X-ray and radium burns, which led to further experimental
studies using laboratory animals in the following decades. The reports of
these experiments and the numerous favourable case histories did not give
conclusive evidence, since although positive results were usually
described, much of the work suffered from poor experimental design and
insufficiently large test samples. In addition some conflicting or
inconsistent results were obtained. With the recent resurgence of
interest in Aloe vera gel, however, new experimental work has indicated
the possibility of distinct physiological effects. Chemical analysis has
shown the gel to contain various carbohydrate polymers, notably either
glucomannans or pectic acid, along with a range of other organic and
inorganic components. Although many physiological properties of the gel
have been described, there is no certain correlation between these and
the identified gel components.
PMID: 3528673 [PubMed - indexed for MEDLINE]
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J Ethnopharmacol. 1999 Dec 15;68(1-3):3-37. Related Articles, Links
Aloe vera leaf gel: a review update.
Reynolds T, Dweck AC.
Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey, UK.
Research since the 1986 review has largely upheld the therapeutic claims
made in the earlier papers and indeed extended them into other areas.
Treatment of inflammation is still the key effect for most types of
healing but it is now realized that this is a complex process and that
many of its constituent processes may be addressed in different ways by
different gel components. A common theme running though much recent
research is the immunomodulatory properties of the gel polysaccharides,
especially the acetylated mannans from Aloe vera, which are now a
proprietary substance covered by many patents. There have also been,
however, persistent reports of active glycoprotein fractions from both
Aloe vera and Aloe arborescens. There are also cautionary investigations
warning of possible allergic effects on some patients. Reports also
describe antidiabetic, anticancer and antibiotic activities, so we may
expect to see a widening use of aloe gel. Several reputable suppliers
produce a stabilized aloe gel for use as itself or in formulations and
there may be moves towards isolating and eventually providing verified
active ingredients in dosable quantities.
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Videre læsning angiver en antibakteriel virkning under specielle
omstændigheder, men ingen virkninger mod astma aller en immunstimulerende
virkning.
--
The individual is the smallest minority.
Med venlig hilsen
Georg
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